ABSTRACT Siddha system of medicine is unique in its own way in treating many acute and chronic ailments. Among the various diseases mentioned, chronic diseases are mainly dealt in Siddha literatures. Many life threatening diseases are also mentioned in it which is becoming more prevalent nowadays. Carcinoma is becoming a major cause of death due to changes and modifications in lifestyle and food practices. Though there are various types of cancers, gastric cancer is becoming more prevalent worldwide and also in our nation. The most common cause for gastric cancer is Helicobacter pylori, which accounts for about 60% of the cases. Other causative factors include smoking, dietary factors etc. Since it causes much threats and drastic effects, the Quality of Life is highly affected. Hence it is the need of the hour to find a proper remedy to manage the symptoms of the disease. Siddha literatures have mentioned about many herbs and minerals which improves the quality of life, serves as a prophylactic agent and also manages the symptoms exhibited by the disease. We have made a formulation using herbal ingredients as per Siddha basic principles and subjected the same to in-vitro anticancer study and found the IC50 value as 135.62µg/ml.

ABSTRACT Indian flora is one of the richest in the world. Siddha system of Medicine greatly depends on this enrich flora to treat diseases. Among them one is the Nyctanthes arbor-tristis L. (Night Jasmine or Pavalamalli), a small tree with its aroma flowers. The leaves of Nyctanthes are given for arthritis, fever, laxative in Siddha. The purpose of this study is to evaluate the acute toxicity potential of Nyctanthes leaves ethanolic extract (NEE) in Wistar albino rats. NEE is evaluated at multiple dose of 100, 500, 1000, 2000 mg/kgbw among four groups for 24 hours orally. While rats in the control group treated with normal saline (5ml/kg). Observations include changes in body weight, irritability, tremor, laboured breathing, staggering, convulsion and death. At the end of the study, biochemical parameters were also estimated. The results indicates safety of oral administration at 100mg/kg bw dose of Nyctanthes leaves and is proved statistically significant (p>0.05). No death is observed in any of the animals.

Kayakarpam is one of the techniques carried out by siddhars to protect our body from death and decay. It is a restorative, constrictive agents which arrest morbific tendencies and decays. Kayakarpam which means anti-oxidant, is an ambrosial medicines taken by the Siddhars for the prevention of death. According to studies on life expectancy, it is revealed that in recent days, it is reduced to the senior age (51-70) due to our lifestyle. This made us to work on this topic to prevent the aging process and diseases. The formulation of “brahmi karpam” was prepared as per the Siddha literature and studied to total antioxidant activity, nitric oxide radical scavenging and hydroxyl radical scavenging. The outcomes of the above assays are furnished in the results.

Siddha system of medicine has its distinctive and remarkable strength in treating Lifestyle disorders. Siddhars have mentioned about many Lifestyle disorders and their treatment modalities in their age-old literatures. One among the lifestyle disorders which is threatening the human beings nowadays is hypercholesterolemia which is referred as Athimetha Noi in Siddha literatures. Elevated levels of cholesterol in the blood may be the consequence of sedentary lifestyle practices or some other diseases or may be familial. The prevalence of hypercholesterolemia is increasing day by day. In the high income countries, one-fourth of the adults are affected. Overall raised cholesterol is found to cause 2.6 million deaths (4.5% of total death) especially because of the consequences of hypercholesterolemia such as Cardio vascular ailments, Hyperglycemia etc. Hence an ideal solution for hypercholesterolemia is a requisite for today’s world. Here in this work, we have made a Poly herbal Siddha Formulation based on the Siddha Basic Principles and subjected to in-vitro anticholesterol assay with special reference to inhibitory activity on the cholesterol esterase.

The literature works of Siddha medicine in Tamil are numerous. In Siddha literature a large number of medicines are involved in the treatment of diseases. Among them, certain medicines are used in the management of infectious diseases. Agents that kill microbes are called microbicidal, while those that merely inhibit their growth are called Biostatic. Antimicrobial resistance has a serious problem due to the massive application of anti biotics, which are used prophylactically or remedially without proper medical indications. The ingredients of the trial drug has proven pharmacological actions such as carminative [Agattuvaai agatri], stimulant[Veppam undakki], anthelmintic [Puzhukkolli] etc, so it can be given to GIT [Gastro Intestinal Tract] disorders, UTI [Urinary Tract Infection]. In this paper, we have given basic study on Anti microbial activity of the trial drug. The drug is effective against some microbes such as gram positive bacteria [eg: Staphylococcus aureus], gram negative bacteria [eg: Proteus vulgaris], fungi [eg: Aspergillus flavus] etc., the Antimicrobial (Anti- bacterial and anti- fungal) activity of Siddha drug is tabulated and high lightened in this paper.

Background: Seendhil (Tinospora cordifolia) is widely used for medicinal purpose. Seendhilsarkkaraihas been used traditionally as anti-hyperglycemic in Siddha System of medicine. Objectives: The present study was undertaken to evaluate the anti–hyperglycemic and anti-hyperlipidemic effects on anti – oxidant enzymes involved in metabolism of seendhilsarkkarai in Streptozotocin induced diabetic rats. Materials and method: Wistar strains of male albino rats weighing between 180-220gm are used for this study. Diabetes mellitus is induced in wistar rats by single intraperitoneal injection of freshly prepared solution of Streptozotocin (25mg/kg BW) in physiological saline after overnight fasting for 12hrs. The body weights of the rats in every group were recorded weekly. five groups of 6 animals in each received normal saline for normal control, glipizide at a dose of (10mg/Kg orally) for diabetic control, SeendhilSarkkarai at a dose of (100mg/Kg orally) and 200mg/kg for euglycemic rat for 28 days,After 28 days of treatment, body weight, blood glucose, haemoglobin, glycosylated haemoglobin, plasma insulin, total cholesterol, triglycerides, HDL-cholesterol and phospholipids and glycogen content and antioxidant enzymes level were determined. Blood was collected from the eyes (venous pool) by sino-ocularpuncture. The data was analyzed statistically using analysis of variance (ANOVA), and the group means were compared by Newman-Keul’s multiple range test (NKMRT) Results: Total cholesterol, triglycerides, high density lipoprotein, Low density lipoprotein (LDL) and phospholipids levels were significantly increased, whereas HDL-C level was decreased in streptozotocin induced diabetic rats as compared to normal rats. Treatment of normal and streptozotocin induced diabetic rats with SeendhilSarkkarai at a dose of 100mg/kg and 200mg/kg (SEENDHIL SARKKARAI) for 28 days resulted in marked decrease in total cholesterol, triglycerides, Low density lipoprotein(LDL) and phospholipids levels and increase in HDL-C levels as compared to streptozotocin induced diabetic rats respectively (P<0.001) as compared to diabetic control. Conclusion: Present study revealed that the seendhilsarkkarai has anti hyperglycemic and anti-hyperlipidemicaction and can be safely used in the treatment of mild to moderate cases of hyperlipidemia.

Attai vidal (leech therapy) is one of the way of bloodletting which comes under the external therapies of Siddha. Leeches have been used for therapeutic purposes before 2000 years by ancient renowned Siddhars. Speckled leech has many active compounds in their saliva. Thus, remove toxins and impure blood and cures many diseases efficiently. This paper discuss about Siddha principles of attai vidal, possible mechanism, guidelines and uses of attai vidal in various ailments narrated in Siddha books and other sources, are concisely discussed in this paper.

The occurrence of gynaecology related disorder is on the raise because of many factors which include socio-economic, environmental and cultural conditions. Young women in their reproductive age are more prone for conditions such as Poly Cystic Ovarian Syndrome (PCOS) which affects their quality of life. PCOS is documented as Sinaipai neerkatti in traditional siddha literatures. At present, the modern medicine treats gynecological disorders especially PCOS with hormone tablets etc., PCOS is the multifaceted problem with reproductive endocrine and metabolic dysfunction. It is also called as Stein-leventhal syndrome. The chemical based drugs induce ovulatory cycle in women, instead of allowing it to restore to its original healthy rhythm. Here we prefer the Siddha medicine “Madhurigai sombu chooranam” as it is wholly natural (herbal), non-invasive, non-chemical remedies and has no side effects. It was prepared as per Standard Operative Procedure (SOP). Preliminary Phyto-chemical analytical study was also done for this medicine. The results serve as an eye opener for further studies in order to identify the potential efficacy of Madhurigai Sombu Chooranam.

The literature works of Siddha medicine in Tamil are numerous. In Siddha literature a large number of medicines are involved in the treatment of diseases. Among them, certain medicines are used in the management of infectious diseases. Agents that kill microbes are called microbicidal, while those that merely inhibit their growth are called Biostatic. Antimicrobial resistance has a serious problem due to the massive application of anti biotics, which are used prophylactically or remedially without proper medical indications. The ingredients of the trial drug has proven pharmacological actions such as carminative [Agattuvaai agatri], stimulant[Veppam undakki], anthelmintic [Puzhukkolli] etc, so it can be given to GIT [Gastro Intestinal Tract] disorders, UTI [Urinary Tract Infection]. In this paper, we have given basic study on Anti microbial activity of the trial drug. The drug is effective against some microbes such as gram positive bacteria [eg: Staphylococcus aureus], gram negative bacteria [eg: Proteus vulgaris], fungi [eg: Aspergillus flavus] etc., the Antimicrobial (Anti- bacterial and anti- fungal) activity of Siddha drug is tabulated and high lightened in this paper.

Siddha System of Medicine was originated from South India, for several centuries as the folk and traditional healing practices of rural Tamilnadu. Over the last several decades, the place for modern Allopathic System of Medicine in many segments of the Health Care System is on worldwide raise, because of its role in managing emergencies. And now, the situation is changed and the whole world is leaping towards the use of Traditional Systems of Medicine, after knowing the benefits of the treatments based on natural origins which include plants, metals, minerals and animals. Hiccups (Diaphragmatic Flutter) is one among the passively increasing diseases, which can be even fatal in patients who experience certain conditions such as the rapid increase in its frequency and severity. Siddha System names the Hiccups as VIKKAL NOI, VIKKUL NOI and EGHAMAA NOI. Many of the treatment aspects available in the Literary form, for the management of Vikkal noi are not in usage . Our work presents a scientific validation of two identical Siddha preparations - a Sastric preparation and a New Relevant Codified Formulation named : “Hiccss Plus ”

Lasuna Thaabitham in siddha (Tonsillitis) is an inflammation of the two oval shaped pads of tissue at the back of the throat. It is mostly caused by bacteria or viral infection. This condition is more prevalent in children. Although self limiting in nature, it is treated by antibiotics and anti inflammatory drugs to avoid clinical manifestations and complications. Chronic condition can be treated by tonsillectomy (surgical removal of the tonsils). In siddha system of medicine, there are many single herbs as well as polyherbal formulations that are effective in the management of lasuna thaabitham. The role of aromatic herbs such as Val milagu (Piper cubeba), Sittrarathai (Alpinia officinarum), Jathikaai (Myristica fragrans),etc. Are note worthy are effective in the treatment of lasuna thaabitham. This paper is intended to study the preparation of Lasuna thaabitha chooranam and also to scientifically validate its efficacy through preliminary anti-microbial and phytochemical analysis of the aforesaid preparation.

Tamarind is a well-known plant in Sri Lanka. There are many literatures had stated about benefits of tamarind. But the effectiveness of Tamarind on the management of Anemia has not established yet. Hence this research had dealt with Anemia on tamarind leaves. This quasi experimental study carried out in 10 patients. In this study Paandu rogam patients were selected based on inclusion criteria at Rural Siddha Ayurvedic Hospital, Kobalapuram. The selected patients were treated with prepared drug for eight weeks. The Patients of between 18 to 60 years of age, both sexes presenting with the signs and symptoms of Anemia were selected randomly based on randomizations schedule. Hemoglobin level was obtained for conformation of Anemic patients in Rural Siddha Ayurvedhic Hospital, Kobalapuram, Trincomalee. All the selected patients were subjected to the detailed history and physical examination on their first visit to the OPD. All the selected patients were treated with 1g of Tamarind leaves choornam powder orally thrice a day for 49 days, and then Evaluation visits were made at 7th, 14th, 21st, 28th, 35th, 42th and 49th days. Effect of treatment was evaluated on the basis of changes in the signs and symptoms after the treatment, then Investigation of Hb level made at 14th, 28th and 49th days. After the treatment patient had statistically significant improvement in Hb level and progressive reduction in sign and symptoms. This shows tamarind leaves chooranam place important role in the management of Paandu rogam

siddha system of medicine

Siddha System of Medicine has a wide range of concepts and basic principles, based on which the pathological, diagnostic and treatment modalities are dealt with. This includes the aspects of Mukkutrangal (Three humors), Arusuvaigal (Six tastes), Pancha bhoothangal (Five elements), etc. In classic Siddha literatures, Many acute and chronic diseases have been well explained in accordance with these basic principles. Some rare disorders are also mentioned in the age-old literatures. One among them is Vikkal noi (Hiccups) which still remains an challenging disorder to treat in the Conventional system of Medicine. Even though it does not cause any drastic effects at the earlier stages, persistent hiccups may lead to serious complications such as Gastro esophageal Reflex Disorder, Sleep disturbances, Arrhythmia, weight loss etc. Though it is a rare disorder, finding a better line of treatment is the need of the hour in order to reduce complications. In this paper we have dealt with the pathological and treatment modalities based upon the Siddha basic principles.

Indian food cuisines greatly depends on traditional cultures, habits, climate, and seasonal variations, individual’s profession, faith and cultivated food stuffs. The art of Indian intellectual customs of nutriment solely rely on Nature which is much advanced and distinguished similar to India’s unique Siddha Medicine as man is the minuscule of the sphere. Siddha Medicine notably italicizes on the dietary patterns derived from the creation. According to them, the three fold combination of the humours (uyir thathukkal) and the object of five senses (Panchabootham) in food, influence the body constituents (udal & uyir thathukkal) and things assimilated in panchabootha human. Through the rules of comestibles, the people can be healthy and defend against illness and deterioration. By visualizing them, a food framework design through Siddha can be created for a perfect eating based on thegi (body type). This article is an effort to bring the Siddha’s concepts of diet, their flavors, properties and its related principles into limelight.

Ancient India gave much important in cleaning and protection of our environment, as it is linked with the people’s behaviour and thoughts. Due to the drastic changes made by industrial development, there is a degradation of natural wealth. Our lives are too polluted just like the environmental pollution and goes on increasing day by day. Enhancement in human health and environmental decline has become a dare today. This can be restrained through the indigenous Siddha medicine which has the basic concept as; man is viewed as a microcosm (Pindam) and the universe as a macrocosm (Andam). So, any peril to the Mother Nature definitely affects the Human. It taught various deeds in maintaining the homeostasis of the man with the environment for a healthy living in which plants play a prestigious role. This paper deliberately summarizes both air (Kaatru) and water (Neer) pollutants, and simpler natural methods by plants for prevention as described in literatures, along with the recent scientific evidences proving that Siddha’s own plants are boon to human race

Nocturnal eneuresis (NE) is an involuntary voiding of urine in sleep otherwise called as bedwetting. It is common in children but adult too, causing social embracement. It is explained under “Sottu Neer” in Siddha literature. Due to psychological, false food habits and false lifestyles may influence this bed wetting. Varmam therapy is the drugless therapy and a state of art of Siddha medical system contributed by the Siddhars for promoting the human health. The vital energy or the Pranan or the vasi spread throughout the body in all its systems including flesh, bone, skin etc,. is known as varmam. It is the better and easiest way for correcting this disorder by stimulating varmam points especially Valampuri and Idampuri kalam in varmam science. Since the child had difficulty in taking oral medicines the simplest external therapy will be more beneficial and it is also cost effective.

In every country traditional medicines find foundation in religious beliefs, experiences and the World Health Organization engaged to establish definite guidelines for methodology of clinical research and the appraisal of effectiveness of traditional medicine. Siddha treatment aims in providing ultimate cure to both mind and body systems. Siddhas developed a discipline called kaya kalpa, leads to longevity and fountain of youth with complete freedom from illnesses. Free radicals cause many diseases. They attack on membranes causing oxidation of lipids, loss of different enzyme activities and may cause cancer. Plants are important source of antioxidants. Antioxidants completely stop or delay the process of oxidation. Pancha kalpa, medicated head bath found in inscriptions (ARE 248/1923) of Vira Rajendra Chola dated on 5th regnal year (1067 Anno Domini) was found by epigraphist K V Subramanya Iyer and mentioned in Pathaarththa guna Sinthamani?. Ingredients are seed of Piper nigrum, rhizomes of Curcuma aromatica, and fruits of Terminalia chebula, Seed of Emblica offinalis, seeds of Azadirachta indica and milk of black cow (Karaampasu) used for both preventive and curative treatments. These counter degenerative changes, which leads to aging by means of the natural antioxidant activity .Here the study focused to explore the efficacy of the drug ensures longevity and freedom from illnesses in inscription and siddha literatures and scientific studies.

Nocturnal eneuresis (NE) is an involuntary voiding of urine in sleep otherwise called as bedwetting. It is common in children but adult too, causing social embracement. It is explained under “Sottu Neer” in Siddha literature. Due to psychological, false food habits and false lifestyles may influence this bed wetting. Varmam therapy is the drugless therapy and a state of art of Siddha medical system contributed by the Siddhars for promoting the human health. The vital energy or the Pranan or the vasi spread throughout the body in all its systems including flesh, bone, skin etc,. is known as varmam. It is the better and easiest way for correcting this disorder by stimulating varmam points especially Valampuri and Idampuri kalam in varmam science. Since the child had difficulty in taking oral medicines the simplest external therapy will be more beneficial and it is also cost effective.

Siddha system is most ancient system of medicine originated from the Southern India which is enriched with flora, fauna and mineral resources. This system of medicine is developed within the Dravidian culture, which is of the pre- vedic period. The prevention and cure of illness are the basic aims of all system of medicine in addition Siddha system is concern for the immortality of the body. Kayakarpam (Elixir Science) is a discipline, which was developed by Siddhars for rejuvenation, longevity and spiritual well being for complete freedom from illness. “Kaya” means body and “Karpam” means stone. It totally means sturdy as a rock and ageless. There are about 108 herbs used in kayakarpam treatment. The drugs are also manufactured from inorganic compounds also. The term kayakarpam has three meanings withstanding the ageing process, maintaining youthfulness and postponement of death until the time one wishes. This requires strict daily regimen in terms of diet and medical supplement. This paper contains details of some rejuvenating herbs and the way of usage to cure certain diseases. The main objective of this paper is to provide information to gain the benefits of rejuvenating herbs at the most.

The Siddha system of medicine, the eldest sibling of all medicine systems has many wonderful and unbelievable curative effects in many diseases. Despite the wrong belief that Siddha line of treatment has no emergency care, this work adds credibility to the emergency management in Siddha which is quoted as “Rana vaithiyam” in Siddha system. This work paves the way for treatment of burn injuries. Fire injury is one of the leading causes of both morbidity and mortality by unintentional injury. Each year more than 3 lakh people die from fire related burn injuries and millions of people suffer from burn related disabilities and disfigurements. In India, over 10 lakh people are moderately or severely burnt every year. So the demand for treatment of burn injury is at its utmost level. This work aims for the treatment in Siddha line, with many remedies. It includes the medicinal preparations for burn wound, promotion of original colour of the skin after injury and to get rid of the scars produced.

Today we are leading a modern life. But, this modern lifestyle pattern mostly affects our health physically, psychologically and socially. Suicidal risk is under high incidence today. In fact, mental, behavioral and substance use disorders are coming to the fore in health care delivery system. So, Management of psychiatric disorders becomes a very important thing in this modern world. Siddha medicine contributes several concepts and treatment methodologies for the management of psychiatric disorders. Kirigai Maruthuvam is the branch of Siddha system of medicine that deals with psychiatry. Siddhars described the symptoms of psychiatric disorders very precisely. Many types of psychiatric disorders were mentioned in several Siddha literatures and they described a lot of types and treatment methodologies which include both internal medicines and a range of external therapies. In this paper, we compared the similarities of signs and symptoms of types of Kirigai (Psychiatric disorders) by Agastiyar with the disease classification given by Yugi muni based on symptoms. This will be a preliminary step in initiating further works on diagnostic criteria of Kirigai in Siddha aspect.

OBJECTIVE : To study the acute toxicity of siddha formulation Uppu Chenduram – II in wistar rats. METHODS : The Uppu Chenduram(test substance) dissolved in distilled water, to be administered at the dosage of 2000 mg/kg/bw. Healthy Wistar rats (5 females) were selected and allowed for an acclimation period of 7 days. The animals were fasted overnight prior to treatment. Feed was made available ad libitum immediately after the treatment. Before commencing the experiment, the body weights of rats were recorded. All the animals were treated with 2000 mg/kg/bw of Uppu Chenduram. The test substance was administered by oral gavage. RESULTS : Single dose oral administration of Uppu Chenduram @ 2000 mg/kg/bw caused no adverse toxic effects on the body weight / body weight changes, feed and the gross anatomy of treated female Wistar rats. The animals did not show any changes in respiration, circulation, autonomic and central nervous system, behavioral pattern. CONCLUSION: The acute oral LD50 of test substance (247) in Wistar rats was observed to be greater than 2000 mg/kg b.w. This indicates the safety of Uppu Chenduram-II through oral administration.

Nosocomial infection by pathogenic bacteria such as Staphylococcus aureus, Streptococcus pneumonia, Klebsiella pneumonia and Escherichia coli deserve special attention in hospital environment because of their frequency and because they are caused by strains resistant to various antibiotics. The aim of the present study is to screen In-vitro Anti-microbial activity of Ayush Siddha formulation against human pathogenic micro organism causing nosocomial infection.

Herbs of Family Zingiberaceae are being widely used as a raw drug in Siddha medicine formulations. It has vast variety of medicinal uses based on their aromatic properties. The Siddha system of medicine is a traditional system generated from Dravidian culture and being served to mankind for more than 2000 years in combating diseases and the maintaining physical, mental and spiritual health. Initially we have collected the medicines to treat Raththapitham from our Siddha literatures. Raththam in Siddha refers to blood. Raththapitham in Siddha refers to elevation of Pitham in blood. Elevation of Pitham in blood results in Hypertension. Raththapitham may be co related with Hypertension. Eventually we can found that most herbs used to treat Raththapitham were from Zingiberaceae. The herbs of Zingiberaceae are used in treating various ailments like diarrhoea, sinusitis, fever, cancer and so on. In this work we have specified the role of those herbs in treating Raththapitham. Hypertension affects about one billion people worldwide. Hypertension is the major cause for cardiovascular diseases worldwide. Globally Cardiovascular disease accounts for approximately 17 million deaths a year. Nearly one third of these Hypertension accounts for about 9.4 million deaths worldwide every year. Hypertension is responsible for at least 45% of deaths due to Heart disease. In 2008, worldwide, approximately 40% of adults aged 25 and above had been diagnosed with Hypertension; the number of people with the condition rose from 600 million in 1980 to 1 billion in 2008. In this work we have notified the wide spread usage of selected 8 herbs of Zingiberaceae to treat Raththapitham (Hypertension).

Bronchial asthma (Iya Iraippu Noi) is a very common disease in the society, due to increasing exposure to air pollution and western life style. It is common in both sexes. The prevalence of bronchial asthma has increased significantly since the 1970s. According to the study in 2025, will expecting more than 300 million people will affect asthma. In the present study, Anti Histaminic and Anti anaphylactic of Lavankathi Chooranam (LC) is investigated in animal models. Antihistaminic activity was studied in guinea pigs using histamine-induced bronchospasm, where pre convulsive dyspnea was used as an end point following exposure to histamine aerosol. It was evaluated for antihistamine and bronchodilator activities and it administrated at the doses of 200 and 400 mg/kg body weight. A dose response curve for histamine is lower, when compared with histamine induced contraction (p<0.05) at moderate dose level. The LC at moderate dose level significantly prolonged the latent period of convulsions as compared to control following the exposure of histamine aerosol. The result of study showed that Lavankathi Chooranam (LC) significantly protected the Guinea pigs against histamine-induced bronchospasm. Significant increase in between pre and post treatment period (**P<0.01). End of the study reveals that the Lavankathi Chooranam (LC) is more effective in the treatment of Bronchial asthma.

Siddhars classified the disease into 4448 types. Among them the disease of nasal origin are 86 and Peenisam is one of them. Peenisam is otherwise known as Mookadaippu or Neerkovai as per Siddha literature and known as Sinusitis in modern medicine. The signs and symptoms of Peenisam according to Siddha literature are thick nasal mucus, plugged nose, fever, headache, sore throat, cough etc. As per records number of adults diagnosed with sinusitis is 29.4 million and percentage of adults diagnosed with sinusitis is 12.1%. Approximately, 0.5% of all upper respiratory tract infection is complicated to sinusitis. Every year 1000 persons are affected by sinusitis. In this review paper we have listed out the commonly identifiable, easily available, cost effective herbs, especially in family Lamiaceae which are against Peenisam. In this paper we have listed out effective herbs against sinusitis in the family Lamiaceae and additional information about peenisam in Siddha literature.

Siddha system of medicine is a well defined science in the medical world. It is one of the most ancient systems of medicine for curing diseases. The symptoms of cervical carcinoma are blood tinged vaginal discharge, painless menorrhagia, malignancy enlarges. This symptom may be correlated with karuppaikazhunthuputtru in our siddha system. Siddhars told a wonderful medicine for karuppaikazhunthuputtru namely Chithira Pallathi Mezhugu. This traditional preparation is being used for ages without scientific validation. In this current study, the attempt is made to establish the fact of anticancer activity of the drug above. In modern scientific approach, this anticancer study can see through In-vitro HeLa cell line method. This cell line method is used for cervical carcinoma. The name HeLa cell line was derived from the name of the lady Henrietta Lacks who had affected by the cervical carcinoma at first. This study results found that the % growth inhibition increasing with increasing concentration steadily up to 30.127µg/ml on HeLa cell line and IC50 value of this assay. Now overall study evaluate that Siddha Formulation ChithiraPallathiMezhugu has potential activity on HeLa cell line. So this drug has considerable anticancer activity on cervical carcinoma.

Siddha medicine is the ancient system of medicine which aims to make the body perfect, imperishable and to promote longevity. Perfect vision is very essential to do day to day activity. But nowadays because of various lifestyle factors many people even children suffer from eye problems. One such problem is Vellezhuthu (Presbyopia). The typical treatment for Vellezhuthu is the use of corrective spectacles or contact lens. This review paper makes an effort to find better treatment for Vellezhuthu as per our Siddha literatures instead of using spectacles for the rest of life. This also explains the use of (Magizham seeds) Mimusops elengi to be administrated with mother’s milk for Vellezhuthu and other medicines. The above said administration contains Vitamin A and Calcium content which is essential for perfect vision. This external medicine is useful in treatment of Vellezhuthu which causes blurred eye, irritated watery eye etc. Vitamin A and Calcium is found to improve vision and rectify blurred vision. This work is an effort to give complete picture of Vellezhuthu as per Siddha texts and its relevance with Presbyopia and to identify the treatment modalities through external medicine by herbal and herbo- mineral preparation.

Treatment of diseases in Siddha system is different and has its own unique feature. Through Siddhars vision, they divided the medicines into 32 Aga (Internal) and 32 Pura(External) medicines. These medicines both prophylactic and therapeutic in nature and also provide immunity. In Siddha system, diseases are classified into 4448.Our body function mainly depends on three states of humor (tridosha). Any changes in the level of tridosha cause disease. IraippuNoi is classified under the division of swasakasam which is one of the divisions of Irumal. IyaIraippu is one of its type which is due to increased Iyam (one of the states of humors). Asthma is very common chronic disease having worldwide prevalence. Asthma is not a contagious disease. It may be due to hereditary, stress and some other reasons. A severe attack of cardiac asthma associated with rapidly developing a pulmonary oedema constitutes one of the commonest and gravest of all emergencies. According to a survey between 100 and 150 million people around the globe suffer from asthma. Worldwide deaths from this condition have reached over 1,80,000 annually. In this review, the signs and symptoms of iyairaippu as found in both Siddha and Modern medicines have been documented.

The Siddha drug Senkaluneer Chooranam (SKC) is used in the treatment of Piththa Diseases (Including Hypertension). This study is evaluated the efficacy and safety of the Siddha drug Senkaluneer Chooranam (SKC) in Albino rats. The Siddha drug SKC its a diuretic effect is found out method in Lipschitz method using frusemide drug as standard. The group – I (Controle Group) was given a normal saline, Group - II (Standard group) serves as standard received the Frusemide (20mg/kg) and the three test groups – III, IV, V were treated by Senkaluneer Chooranam (SKC) doses level of 100mg/kg, 200mg/kg, 300mg/kg respectively. Albino rats were kept in metabolic cages and 24 hours urine was collected. Total urine volume and urinary excretion of measured using a standard measuring cylinder. SKC has secreted dose dependant increase volume in total urine volume, when compare to control group. The test drug Senkaluneer Chooranam at the dose levels of 100mg/kg, 200mg/kg and 300 mg/kg, which its showed a statistically significant increase in the volume of urine with a dose dependent increase in the diuretic Urine volume to 10.28, 13.58 and 14.37 respectively. The drug also confirmed a significant increase in sodium excretion in comparison to control group. An increase (p ? 0.05) in urinary excretion of potassium is also observed. The Senkaluneer Chooranam (SKC) treated rats showed high diuretic effect as compared to control but this effect is less than the frusemide (Group II). So, Senkaluneer Chooranam (SKC) is good diuretic activity.

Siddha system is one of the ancient traditional systems of medicine for treating various disease conditions by the herbals and herbo – mineral drugs. Today, there is a need to evaluate our ancient knowledge on modern parameters to establish Siddha medicine as a main stream medical science. Standardization are essential analytical tools to upgrade the medicine. FTIR showed the peak values which are the functional groups present. Ayakantha Chendhuram is used in the treatment of various disorders especially Anaemia (Paandu noi) and its related pathological conditions. The aim of the present study was to standardize the Siddha herbo – mineral formulation (Ayakantha Chendhuram) by doing the Fourier Transform Infrared Spectroscopy (FTIR) and the results were noted. This study will highlight the functional groups by using the standardizing technique for the herbo – mineral formulation and brings it to the next level of research.

Siddha system is one of the ancient system of medicine. In this system the knowledge of drugs is not only limited to herbs, but also expands to metals and minerals. Kalamega narayana chendhooram (Kmnc referenced from classical text Chikichcha Raththina Theepam ennum Vaiththiya Nool Authored by Vaiththiya Viththuvan. Mani S.Kannuchamipillai Pp. 247, Published B.Rathnanayakar and Sons, Chennai – 600 079) is one of the minero metallic formulation which is indicated for the treatment of more than three hundred diseases. Standardization of Siddha drug is a burning topic in herbal drug industry today. Standardization is difficulty because the Siddha formularies are usually mixtures of many constituents and the active principle in most cases is unknown, however, it is possible to generate a physico - chemical finger print for the standardization

The Siddha drug Ingi chooranam (IC) is used in treating of vatha diseases. The aim of the study was to investigate the efficacy of the Siddha drug Ingi chooranam (IC) in swiss albino mice. The analgesic effect was found out by Acetic acid writhing reflex method using diclofenac sodium as standard drug. The control group-I was given normal saline, group-II serves as standard received diclofenac sodium (10 mg/kg) and the two test groups –III, IV are treated by Ingi chooranam (IC) at dose level of 100mg/kg, 200mg/kg respectively. One hour before acetic acid administration Siddha formulation Ingi chooranam was administed. Onset on writhing is noted. Contractions of the abdomen, twist of the trunk, hind limbs extension were noted within 10 minutes how many animals showing such response were also noted and the result reveals that the both doses of Ingi chooranam possess significant analgesic activity

“Do your duty and leave the rest to God” is the essence of the Bhagavat Gita. Selfless service for a right cause and completely focusing towards it without any expectation should be the ultimate aim. The outcome of any work will be positive only when the work is done selflessly without any expectation. Disinterested work will not pave way to the achievement the goal. One should deeply get involved in any action which he/she is doing. We should overcome the obstacles in order to reach the destination. The destination is nothing but the eternity. Siddhars have mentioned about Gnyaana and Kanma Yogam in their Literatures and also they have followed it to attain the eternity. In the literatures, it is mentioned as Gnyaana maarkkam and kanma maarkkam. Each and every man should follow Kanma Yogam and should not deviate from that so as to maintain peace and health. In this paper, we have mentioned about the Kanma Yogam, their outcomes and benefits, Kanma diseases based on Siddha texts, and their corrective measures (Kanma nivarthi) and the current scenario.

Nowadays, most of the people are facing eye diseases like vision problem, burning sensation of eye, cataract, redness of eye, Night blindness and etc. The most of the eye diseases cured in modern medicine are by wearing lens and surgery. In Siddha, Siddhars prescribed some herbs to cure the eye diseases without surgery. General usage of the term “herb” differs between culinary herbs and medicinal herbs. Any parts of the plant might be considered as “herbs” including leaves, roots, flowers, seeds, root bark, inner bark (cambium), resin and pericarp. Tabernaemontana divaricata, Alternanthera sessilis, Eclipta prostata, Strychnus potatorum, Phyllanthus emblica, Azadirachta indica were used in the eye disease. It cure the eye diseases without any adverse effect. Eye diseases can cause damage and blindness if not treated soon enough. This review deals about some particular herbs among eye disease herbs for their specificity. This work will be helpful for better therapy to eye disease and further studies in future.